John Boukouvalas, professeur titulaire
Pavillon Alexandre-Vachon, local 1413
T. 418 656-5473
F. 418 656-7916
john.boukouvalas@chm.ulaval.ca
Champs d'intérêts
  • Synthèse de produits naturels
  • Nouvelles méthodes de synthèse
  • Chimie verte et catalyse asymétrique
  • Chimie médicinale

Publications

Pour la liste complète, consultez ResearchGate.

  • «Concise Total Synthesis of (–)-Auxofuran by a Click Diels-Alder Strategy», J. Boukouvalas and R. P. Loach, Org. Lett.2013, 15, 4912–4914.
  • «Aminolactone Chiral Modifiers for Heterogeneous Asymmetric Hydrogenation: Corrected Structure of Pantoyl-Naphthylethylamine, In-Situ Hydrogenolysis, and Scanning Tunneling Microscopy Observation of Supramolecular Aminolactone/Substrate Assemblies on Pt(111)», G. Goubert, V. Demers-Carpentier, R. P. Loach, R. Lafleur-Lambert, J.-C. Lemay, J. Boukouvalas and P. H. McBreen, ACS Catal. 2013, 3, 2677-2683.
  • «Short, Enantioselective Total Syntheses of Fugomycin and Desoxyfugomycin via Sonogashira Alkynylation of ?-Bromobutenolides», J. Boukouvalas and N. Bruneau-Latour, Synlett 2013, 24, 2691–2694.
  • «Biomimetic Synthesis of Antrodia Maleimides and Maleic Anhydrides», J. Boukouvalas and V. Albert, Heterocycles 2014, 88, 939-944 (V. Snieckus Special Issue).
  • «Unified Route to Asymmetrically Substituted Butenolide, Maleic Anhydride and Maleimide Constituents of Antrodia camphorata»m, J. Boukouvalas, V. Albert, R. P. Loach and R. Lafleur-Lambert,Tetrahedron 2012, 68, 9592–9597.
  • «Regiospecific Synthesis of Cepanolide, a Cancer Chemoprotective Micronutrient Found in Green Onions», J. Boukouvalas and V. Albert, Tetrahedron Lett. 2012, 53, 3027–3029.
  • «Direct Observation of Molecular Preorganization for Chirality Transfer on a Catalyst Surface», V. Demers-Carpentier, G. Goubert, F. Masini, R. Lafleur-Lambert, Y. Dong, S. Lavoie, G. Mahieu, J. Boukouvalas, H. Gao, A. M. H. Rasmussen, L. Ferrighi, Y. Pan, B. Hammer and P. H. McBreen, Science 2011, 334, 776-780.
  • «Synthesis of the Hypoxic Signaling Inhibitor Furospongolide», J. Boukouvalas and V. Albert, Synlett 2011, 2541-2544.
  • «Oxidative Rearrangement of 2-Furylcarbamates with Dimethyldioxirane: a High-yielding Preparation of 5-Hydroxypyrrol-2(5H)-ones», J. Boukouvalas, R. P. Loach and E. Ouellet, Tetrahedron Lett. 2011, 52, 4636-4639.
  • «Concise, Regiocontrolled Synthesis of Yangjinhualine A», J. Boukouvalas and L. C. McCann, Tetrahedron Lett. 2011, 52, 1202-1204.
  • «Synthesis of the Human Aldose Reductase Inhibitor Rubrolide L», J. Boukouvalas and L. C. McCann, Tetrahedron Lett. 2010, 51, 4636-4639.
  • «General, Regiodefined Access to a-Substituted Butenolides through Metal-Halogen Exchange of 3-Bromo-2-silyloxyfurans. Efficient Synthesis of an Anti-inflammatory Gorgonian Lipid», J. Boukouvalas and R.P. Loach, J. Org. Chem. 2008, 73, 8109-8112.
  • «Structure Revision and Synthesis of a Novel Labdane Diterpenoid from Zingiber ottensii», J. Boukouvalas and J.-X. Wang, Org. Lett. 2008, 10, 3397-3399.
  • «Dimethyldioxirane Oxidation of 2-Silyloxypyrroles: An Efficient Regiocontrolled Synthesis of 5-Hydroxy-3-pyrrolin-2-ones», J. Boukouvalas, Y. Xiao, Y.-X. Cheng and R. P. Loach, Synlett 2007, 3198-3200.
  • «Expedient Synthesis of Villosin and its Isomer (E)-Labda-8(17),12,14-trien-15(16)-olide», J. Boukouvalas, J.-X. Wang and O. Marion, Tetrahedron Lett. 2007, 48, 7747-7750.
  • «A Concise Asymmetric Synthesis of (+)-Muscarine from (S)-g-Hydroxymethyl-g-butyrolactone», J. Boukouvalas and I.-I. Radu, Tetrahedron Lett. 2007, 48, 2971-2973.
  • «A New, Highly Stereoselective Synthesis of b-Unsubstituted (Z)-g-Alkylidenebutenolides Using Bromine as a Removable Stereocontrol Element», J. Boukouvalas, P. P. Beltrán, N. Lachance, S. Côté, F. Maltais, M. Pouliot, Synlett 2007, 219-222.
  • «Facile Access to 4-(1-Alkynyl)-2(5H)-furanones by Sonogashira Coupling of Terminal Acetylenes with b-Tetronic Acid Bromide: Efficient Synthesis of Cleviolide», J. Boukouvalas, S. Côté and B. Ndzi, Tetrahedron Lett. 2007, 48, 105-107.

Formation et expériences professionnelles

  • Maître-assistant, University of Geneva, 1986-1992
  • Research Associate, University of Geneva, 1981-1986
  • Postdoctoral Fellow, University of Warwick, 1980-1981
  • Ph. D. chimie, University of Birmingham, 1980
  • B. Sc. chimie, University of Leicester, 1977
 
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